In the couple’s second IVF routine, eight of 17 eggs had been fertilized, and two embryos had been frozen. The findings were presented on Monday at the American Society for Reproductive Medication annual meeting in Baltimore. The study was published simultaneously in the journal Fertility and Sterility. During 2013, the U.S. Centers for Disease Control and Prevention reported that nearly 191,000 assisted reproductive technology cycles had been performed in the United States.A potential concern may be the misclassification of the exposure or the outcome, since nondifferential misclassification shall tend to bias outcomes toward the null.28 Documentation a prescription was packed does not promise that the medication was actually taken as prescribed. However, secondary analyses in which we required women to have stuffed or refilled a prescription during the first trimester didn’t substantially alter the findings, although the estimates had been less precise due to the reduced cohort size.