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The results claim that recruitment of fresh capillaries could be a leading event mixed up in improvement of CI. This study was the first to demonstrate the infusion of the combination cell product was safe and feasible. The formation of new mature blood vessels with the ability to appropriate blood supply to the heart is complex and requires participation of several types of adult stem cells and growth factors. The Stage II study further investigates the safety and efficacy of intracoronary infusion of a combination cell product. The researchers believe that the usage of adult stem cell therapy in limb and coronary ischemia sufferers permits the development of fresh mature and stable capillaries.