Aging-linked protein deficiency might trigger positive breast cancer in women The most common kind of breast cancer in older women – estrogen and progesterone receptor positive breast cancer – has been linked to a protein that fends off aging-related cellular damage. A new study led by Vanderbilt-Ingram Tumor Center researcher David Gius, M suhagra .D., Ph.D., now shows how a insufficiency in this aging-associated protein may collection the stage for these tumors to develop. The findings, released in Molecular Cell, offer information that could help out with the screening, treatment and prevention of these common age-related cancers.
Aging in mice at the molecular level Researchers at the National Institute of Aging and Stanford University have got used gene arrays to recognize genes whose activity adjustments with age in 16 different mouse cells. The study, published November 30 in PLoS Genetics, runs on the newly available data source called AGEMAP to record the process of aging in mice at the molecular level. The ongoing work describes how aging affects different tissues in mice, and ultimately could help explain why lifespan is limited to just 2 yrs in mice. As an organism age range, most tissues modification their structure , and all tissues are subject to cellular harm that accumulates with age group. Both changes in tissues and cellular damage lead to changes in gene expression, and therefore probing which genes transformation expression in old age can lead to insights about the process of maturing itself.